PEEK Physical Surface Modification: Evaluation Of Particles Leaching Process

Polyetheretherketone (PEEK) has been prominent in orthopedic implants; however, it is inert, preventing interaction between the implant and adjacent bone tissues. One way to overcome this characteristic is physical modification its on surface by particle leaching promoting greater osseointegration. The objective of this research was to develop and characterize the PEEK using a surface modification technique via particle leaching. For of the samples, a layer deposition of NaCl was used on PEEK. This was subjected to the pressure of 850 kg/cm2 by 390ºC for 20 minutes. After cooling, were subjected to leaching process particles. The results indicated a porous surface exhibiting uniform and homogeneous morphology with defined pores interconected, to in the range of 140-373 µm, with an average diameter of 273 µm. These evidenced the considerable NaCl removal after the leaching process, with cavities from ideal sizes which promotes adequate cellular accommodation and distinct roughness, giving an overall possibility of being able to obtain a material more able to receive the cells while also possibly presenting cell viability. Although the compressive strength presented low values, it can still be suitable for applications in areas with a reduced modulus of elasticity.

聚醚醚酮（Polyetheretherketone, PEEK）在骨科植入物领域一直占据重要地位，但其本身具有生物惰性，无法实现植入物与邻近骨组织之间的相互作用。克服这一特性的一种可行方案是对其表面进行物理改性，通过颗粒沥滤（particle leaching）技术促进更佳的骨整合（osseointegration）效果。本研究旨在采用颗粒沥滤表面改性技术制备并表征PEEK材料。对于所有样品，先在PEEK基体表面沉积NaCl层，随后将其置于850 kg/cm²压力、390℃的环境中保温20分钟。冷却后，对样品进行颗粒沥滤工序。结果表明，改性后的表面呈现均匀一致的多孔形貌，孔隙界定清晰且相互连通，孔径分布范围为140~373 μm，平均孔径为273 μm。实验结果证实，沥滤过程中NaCl得以大量去除，所形成的空腔尺寸适宜，可促进细胞良好附着，且表面粗糙度适中；整体而言，该材料不仅能够为细胞黏附提供优良环境，还可能具备良好的细胞活性。尽管该材料的抗压强度较低，但仍可适用于弹性模量要求较低的应用场景。