PHYTOCHEMICAL ANALYSIS AND EVALUATION OF PHARMACEUTICAL INDICATORS OF PAEONIA LACTIFLORA AND GINKGO BILOBA

Medicinal plants play an important role as sources of biologically active compounds in the pharmaceutical industry. This study is aimed at analyzing the phytochemical composition of Paeonia lactiflora and Ginkgo biloba and evaluating their pharmaceutical parameters. In the course of the study, Paeonia lactiflora roots and Ginkgo biloba leaves were used as plant raw materials. The results of the phytochemical analysis revealed the presence of flavonoids, phenolic compounds, and glycosides in both plants. Ginkgo biloba was distinguished by its high content of flavonoids and phenolic compounds, while Paeonia lactiflora showed a high level of monoterpene glycosides, particularly paeoniflorin. The presence of the main biologically active compounds was confirmed using thin-layer chromatography (TLC) and high-performance liquid chromatography (HPLC). During the evaluation of pharmaceutical parameters, moisture content, total ash, and extractive values were determined, and their compliance with pharmacopoeial requirements was confirmed. The obtained results indicate that Paeonia lactiflora and Ginkgo biloba are promising for use in pharmaceutical practice.药用植物作为生物活性化合物的重要来源，在制药工业中具有关键作用。本研究旨在分析芍药（Paeonia lactiflora）与银杏（Ginkgo biloba）的植物化学组成，并评估其药学参数。本研究以芍药根与银杏叶作为植物原料开展实验。 植物化学分析结果显示，两种供试植物中均含有黄酮类、酚类化合物及苷类成分。其中银杏（Ginkgo biloba）的黄酮类与酚类化合物含量较高，而芍药（Paeonia lactiflora）则含有高水平的单萜苷类成分，尤以芍药苷（paeoniflorin）为代表。主要生物活性成分的存在经薄层色谱（thin-layer chromatography, TLC）与高效液相色谱（high-performance liquid chromatography, HPLC）验证确认。 在药学参数评估环节，本研究测定了水分含量、总灰分及浸出物值，并证实其符合药典相关要求。本研究结果表明，芍药（Paeonia lactiflora）与银杏（Ginkgo biloba）在制药实践中具备良好的应用前景。