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GSK3 inhibitor testing of AML cells
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创建时间:
2016-06-29
相关数据集
Genetic and chemical targeting of the ATPase complex TIP48 and 49 impairs acute myeloid leukemia
The chromatin-associated AAA+ ATPases Tip48 and Tip49 are the core components of various complexes implicated in diverse nuclear events such as DNA repair and gene regulation. Although they are freque
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Activity of the isolated polyacetylenes towards the three subtypes of human PPAR (α, β/δ, γ) in a luciferase reporter transactivation assay.
n.d. not detected up to 30 µM.HEK-293 cells transiently co-transfected with the respective PPAR subtype expression plasmids, a luciferase reporter plasmid (tk-PPREx3-luc), and EGFP as internal control
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MMV001239 Drug Selected Yeast Strains. Saccharomyces cerevisiae S288c
ABC16-Monster drug-sensitive yeast strain was selected for resistance to MMV001239
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Additional file 2: of Co-inhibition of HDAC and MLL-menin interaction targets MLL-rearranged acute myeloid leukemia cells via disruption of DNA damage checkpoint and DNA repair
Table S1. List of all genes that were differentially expressed in cells exposed to MI-3, chidamide, or both, in which 635 overlapped genes shown in the Venn Diagram (Figure 3C) as well as 59 genes ind
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