Role and diagnostic performance of host epigenome in respiratory morbidity after RSV infection: the EPIRESVi study. Role and diagnostic performance of host epigenome in respiratory morbidity after RSV infection: the EPIRESVi study

Infinium MethylationEPIC was used to analyze the DNA methylation changes related to the development of wheezing and / or asthma induced after RSV infection. Overall design: DNA was extracted from whole blood collected from 77 participants. The treated DNA was hybridized to the Illumina Infinium MethylationEPIC BeadChip.

本研究采用Infinium甲基化EPIC芯片（Infinium MethylationEPIC），分析呼吸道合胞病毒（RSV）感染后诱发的喘息及/或哮喘发病进程相关的DNA甲基化改变。整体实验设计：从77名受试者的全血样本中提取基因组DNA；将经处理的DNA与Illumina Infinium甲基化EPIC微珠芯片（BeadChip）进行杂交。