ATN 004 CAPI #5: Readiness Ruler Dataset in Healthy Choices: Motivational Enhancement to Promote Health and Reduce Risk in HIV-Infected Youth

Data from CAPI #5: Readiness Ruler
Study Description
In this Phase II multi-site clinical trial, HIV+ youth were randomized to receive either a four-session motivational enhancement intervention and referrals or standard care plus referrals. Participants randomized to the intervention group participated in four sessions of Healthy Choices, a motivational enhancement intervention specifically designed to target multiple risk behaviors in HIV+ youth. Participants received individualized referrals at the fourth session. Participants randomized to standard care also received individualized referrals. Interviews, self-report, chart review and blood tests were used to measure substance use, condom use, adherence to medications, and health outcomes, as well as hypothesized mediators and moderators of the intervention. The primary objective was to determine the efficacy of a motivational enhancement intervention in reducing health risk behaviors (drug and alcohol use, sexual risk behavior, poor adherence to medications) among HIV+ youth. HIV+ youth ages 16 to 24 years, engaged in two out of three problem behaviors (substance use, sexual risk behavior, or poor medication adherence)

CAPI #5数据集：准备度量表（Readiness Ruler）
研究描述
本项多中心II期临床试验中，HIV阳性（HIV+）青少年被随机分为两组：一组接受4次动机强化干预（motivational enhancement intervention）与转介服务，另一组接受标准护理联合转介服务。
干预组参与者完成了4次「健康选择（Healthy Choices）」课程——该方案为专门针对HIV阳性青少年多重风险行为设计的动机强化干预项目，并在第4次课程中获得个性化转介服务。标准护理组参与者同样可获得个性化转介服务。
研究通过访谈、自我报告、病历审查及血液检测，对物质使用、安全套使用、服药依从性与健康结局进行评估，同时检验该干预的潜在中介变量与调节变量。
本研究的主要目标为验证动机强化干预在降低HIV阳性青少年健康风险行为（药物与酒精使用、性风险行为、服药依从性不佳）方面的有效性。
本研究纳入的受试者为16至24岁的HIV阳性青少年，且存在三类问题行为中的两类：物质使用、性风险行为或服药依从性不佳。