Identification of enhancer-promoter contacts in squamous cancer cells [ChIP-seq]

Profiling the histone modification H3K27ac, the co-activator BRD4 and the transcription factor SOX2 in squamous cancer cell lines Overall design: Chromatin Immunoprecipitation-sequencing (ChIP-seq) of H3K27ac, BRD4 and SOX2 in squamous cancer cell lines

对鳞状癌细胞系中的组蛋白修饰H3K27ac、共激活因子BRD4以及转录因子SOX2进行谱型分析。整体实验设计：针对鳞状癌细胞系中的H3K27ac、BRD4及SOX2开展染色质免疫共沉淀测序（Chromatin Immunoprecipitation-sequencing，ChIP-seq）。