Behavioral and psychosocial predictors of depression in Bangladeshi medical students: a cross-sectional study

This cross-sectional study was conducted from July to November 2021, among students from four public medical colleges chosen at random from among 37 public medical colleges in Bangladesh. The sample size was determined based on a 95% confidence interval and a 5% sampling error. The needed sample size to estimate a true prevalence of depression was computed using "Epitools" (https://epitools.ausvet.com.au/prevalencess). Assuming the prevalence of depression among medical students of 39.1 and sensitivity 74 percent and specificity 91 percent for PHQ9, the estimated sample size was 838. We enrolled 840 medical students using two-step stratified random sampling from a total of 5000 medical students from selected medical colleges; 210 students from each of the medical colleges, and 42 students from each year were selected randomly from each year from first to fifth year. The pretested Bengali version of the questionnaire was translated and back-translated by two independent bilingual translators to check the consistencies avoiding response bias. The self-rated survey took approximately twenty minutes. Before implementing the survey, formal permission from the IRB as well as written consent from the participants were taken. After checking for inconsistencies and missing values, all 840 data were found to have completed the entire survey and were entered into the spss v-23 software for further analysis. The purpose of this study was to determine the prevalence of depression among medical students at Public Medical Colleges as well as implicit depression predictors such as anxiety, perceived stress, internet addiction, Facebook addiction, sleep quality, sociodemographic and behavioral factors.

本横断面研究于2021年7月至11月间开展，研究对象为孟加拉国37所公立医学院校中随机抽取的4所公立医学院校的学生。样本量基于95%置信区间与5%抽样误差确定：本研究采用Epitools工具（https://epitools.ausvet.com.au/prevalencess）计算了估算抑郁症真实患病率所需的样本量。假设医学生抑郁症患病率为39.1%，且患者健康问卷9项（PHQ9）的灵敏度为74%、特异度为91%，最终估算样本量为838。本研究从入选医学院校的5000名医学生中，采用两阶段分层随机抽样法招募了840名医学生：每所医学院校抽取210名学生，再从一年级至五年级的每一年级中随机抽取42名学生。本研究采用经过预试验的孟加拉语版问卷，由两名独立的双语翻译人员分别进行翻译与回译，以检验问卷一致性并规避应答偏倚。本次自评式调查耗时约20分钟。正式开展调查前，本研究已获得机构审查委员会（IRB, Institutional Review Board）的正式批准，并获取了所有参与者的书面知情同意。在核查数据一致性与缺失值后，全部840份数据均完成了完整调查，随后将数据导入SPSS v23统计软件进行后续分析。本研究旨在明确公立医学院校医学生的抑郁症患病率，并探讨抑郁症的潜在预测因素，包括焦虑、感知压力、网络成瘾、脸谱网（Facebook）成瘾、睡眠质量、社会人口学特征与行为因素。