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Summary of anti-RBPJ ChIP-seq results.

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Figshare2015-12-02 更新2026-04-29 收录
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https://figshare.com/articles/dataset/_Summary_of_anti_RBPJ_ChIP_seq_results_/953744
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1A specific peak was defined as having enrichment within a 200 bp region of more than 4-fold between the two cell populations and a Poisson enrichment p-value2A common peak was defined as having similar enrichment between mitotic and asynchronous peaks. As we observed peak shifting (see Figure 4), common peaks were centered on asynchronous peaks. If centered on mitotic peaks, 8.2% and 8.4% of common peaks contain RBPJ and CTCF motifs, respectively.

1A 特异性峰(specific peak)的定义为:在200碱基对(base pair, bp)区域内,两种细胞群之间的富集倍数超过4倍,且具有泊松富集p值(Poisson enrichment p-value)。 2A 共有峰(common peak)的定义为:有丝分裂细胞峰与非同步细胞峰之间的富集程度相似。鉴于研究中观察到峰移位现象(详见图4),共有峰以非同步细胞峰为中心。若以有丝分裂细胞峰为中心,则分别有8.2%和8.4%的共有峰包含RBPJ(Recombination signal binding protein for immunoglobulin kappa J region)基序与CTCF(CCCTC-binding factor)基序。
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2015-12-02
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