Porphyromonas-gingivalis-enriched microcosm biofilms

The aim of this study is to develop a high-throughput in vitro biofilm model that mimics dysbiotic subgingival microbiota by incorporating the major periodontal pathogen Porphyromonas gingivalis into microcosm biofilms cultured from pooled saliva of healthy volunteers

本研究旨在构建一种高通量体外生物膜模型，通过将主要牙周致病菌牙龈卟啉单胞菌（Porphyromonas gingivalis）引入由健康志愿者混合唾液培养得到的微群落生物膜中，以模拟生态失调的龈下微生物群。