Supplemental Table S1. Descriptive statistics of the systematic effects and datasets

Genetic and phenotypic (co)variances of hematological parameters were performed with 1,610 genotype data and 5,499 hematological parameter records from 4,543 cows, using the Average Information Restricted Maximum Likelihood method. Also, we assessed the genetic relationship among these indicators and other economically important traits in dairy cattle breeding. Finally, we carried out genome-wide association studies and candidate gene analyses, and blood samples from 21 primiparous cows were used for further validation of candidate genes through RNA sequencing (<b>RNA-seq</b>) analyses.

本研究利用来自4543头奶牛的1610份基因型数据与5499条血液学参数记录，采用平均信息约束极大似然（Average Information Restricted Maximum Likelihood）法开展了血液学参数的遗传及表型（共）方差分析。此外，本研究还评估了上述血液学指标与奶牛育种中其他经济重要性状之间的遗传相关性。最后，本研究开展了全基因组关联分析与候选基因分析，并选取21头初产奶牛的血液样本，通过RNA测序（RNA-seq）分析对候选基因进行进一步验证。