Global Milk

The human milk microbiota is a complex biologically active component of human milk, and many factors may influence its composition. Until now, most culture-independent assessments of the diversity of the human milk microbiota have been carried in small cohorts and/or in single geographical locations. In addition, most of the studies performed so far have been restricted to the bacteriome. This study aimed to assess the bacterial and fungal composition of human milk and the potential inter-kingdom interactions in milk samples collected from women living in a wide spectrum of countries, environments and socio-economical settings.

人乳微生物组（human milk microbiota）是人乳中一类复杂且具有生物活性的组分，其组成可受诸多因素影响。迄今为止，绝大多数针对人乳微生物组多样性的非培养依赖型评估，均基于小型队列或仅在单一地理区域开展。此外，截至目前的多数相关研究仅局限于细菌组（bacteriome）范畴。本研究旨在对覆盖多国、多环境与多社会经济背景的女性所采集的人乳样本，分析其中的细菌与真菌组成，并探究其潜在的跨界相互作用。