Gcn5 and Bre1-mediated Set2 degradation promotes chronological aging of Saccharomyces cerevisiae Yu-Min Li et al.

This study demonstrates two sequential post-translational modifications regulate Set2 homeostasis, which is required for sustaining extended chronological lifespan of yeast. The dataset includes 3 zip files, including main Figures 1-7, supplementary Figures 1-9, and original data of mass spectrometry. All original data encompass images of Western blots and gels, and quantitative numbers are shown in the decompressed excel files.

本研究证实，两种连续的翻译后修饰（post-translational modifications）可调控Set2稳态，而该稳态是维持酵母延长时序寿命所必需的。本数据集包含3个ZIP压缩包，分别涵盖主图1-7、补充图1-9以及质谱（mass spectrometry）原始数据。所有原始数据均包含蛋白质免疫印迹（Western blots）与凝胶电泳图像，定量数据则见于解压后的Excel文件中。