Exploring the link between inflammation and brain function after metabolic-bariatric surgery: A year-long fMRI study
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https://repod.icm.edu.pl/citation?persistentId=doi:10.18150/OCXMUZ
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资源简介:
This dataset originates from a longitudinal observational study investigating the interplay between inflammation and brain function following laparoscopic sleeve gastrectomy (LSG). It includes raw neuroimaging data and extensive clinical and biochemical metadata from 36 participants assessed at three time points:1 week before surgery (Session 1)3 months after surgery (Session 2)12 months after surgery (Session 3)Contents:1. Raw neuroimaging data (NIfTI format) - Structural MRI: T1-weighted anatomical scans - Functional MRI: 5-minute resting-state scans (TR = 2.5s, 120 volumes)2. Spreadsheet (BAR22_DOM.xlsx) This Excel file includes:- Participant demographics: age_y, female_gender- Comorbidities: type_2_diabetes, hypertension, hypothyroidism, insulin_resistance, depression- Metabolic measures: HDL_baseline_mgdl, triglycerides_mgdl, HOMA_IR, etc.- Cytokine levels: IL-6 and IL-10 values and derived metrics such as:- IL_6_by_IL10, IL_10_by_IL6- Log-transformed ratios (e.g., IL_6_by_IL10_log)- Baseline-normalized cytokine ratios- Session information: Each row corresponds to a subject-session pair (Subject, Session)
本数据集源自一项纵向观察性研究,旨在探究腹腔镜袖状胃切除术(laparoscopic sleeve gastrectomy, LSG)后炎症反应与脑功能之间的相互作用。数据集涵盖36名受试者在三个时间点的原始神经影像数据以及全面的临床与生化元数据,三个时间点分别为:术前1周(第1次访视)、术后3个月(第2次访视)、术后12个月(第3次访视)。
数据集内容如下:
1. 原始神经影像数据(NIfTI格式)
- 结构磁共振成像:T1加权解剖扫描
- 功能磁共振成像:5分钟静息态扫描(重复时间TR=2.5秒,共120帧影像)
2. 电子表格文件(BAR22_DOM.xlsx)
该Excel文件包含以下内容:
- 受试者人口统计学信息:年龄(age_y)、女性性别(female_gender)
- 合并症情况:2型糖尿病、高血压、甲状腺功能减退、胰岛素抵抗、抑郁症
- 代谢指标:基线高密度脂蛋白胆固醇(HDL_baseline_mgdl)、甘油三酯(triglycerides_mgdl)、胰岛素抵抗指数HOMA-IR等
- 细胞因子水平:白细胞介素-6(IL-6)与白细胞介素-10(IL-10)的检测值及衍生指标,具体包括:
- IL-6/IL-10比值、IL-10/IL-6比值
- 对数转换后的比值(如IL_6_by_IL10_log)
- 以基线为参照的细胞因子比值
- 访视信息:每一行对应一名受试者的一次访视,包含字段:受试者编号(Subject)、访视编号(Session)
提供机构:
RepOD
创建时间:
2025-05-26



