Recombination at subtelomeres is regulated by physical distance, double strand break resection and chromatin status

Two conditions experiment, ChIP-chip anti-Sir3 comparing Sir3 occupancy in exponentially growing S.cerevisiae cells to Sir3 occupancy in strains overexpressing SIR3本实验为双条件对照实验，采用抗Sir3抗体（anti-Sir3）的染色质免疫沉淀芯片（ChIP-chip）技术，对比指数生长期酿酒酵母（Saccharomyces cerevisiae，简称S.cerevisiae）细胞中Sir3蛋白的染色质结合丰度，与过表达SIR3基因的酿酒酵母菌株中的Sir3蛋白染色质结合丰度。