Marijuana and pregnancy: cannabis hyperemesis syndrome - Case report

ABSTRACT The authors report a case from the psychiatric department of a general hospital (Santa Casa de Misericordia at Sorocaba city, São Paulo, Brazil). A patient, 19-year-old, pregnant woman, marijuana chronic user, presenting abdominal pain, psychomotor agitation, unmanageable nausea, severe vomiting, not responsive to antiemetic drugs, associated with compulsive hot water showering. Cannabinoid hyperemesis syndrome is sub-diagnosed and rare, characterized by those three symptoms: heavy marijuana use, vomiting and repeated hot showering. There is no prior report in Brazilian medical literature. This paper aims to emphasize the importance of recognizing and categorizing this syndrome and its correlation to marijuana use. Main treatment is supportive care, withdrawing substance and supportive carries to suspension of marijuana use as well as clinical complications prevention.

摘要 作者报告了一例来自巴西圣保罗州索罗卡巴市圣卡萨德米塞里科迪亚综合医院精神科的病例。患者为19岁孕妇，长期吸食大麻，表现为腹痛、精神运动性激越、难以控制的恶心及严重呕吐，且对止吐药物无应答，同时伴有强迫性热水淋浴行为。大麻素性呕吐综合征（Cannabinoid Hyperemesis Syndrome）常被漏诊且较为罕见，其特征为三大典型症状：大量吸食大麻、呕吐及反复热水淋浴。巴西医学文献中此前尚无相关报道。本文旨在强调识别并分类该综合征及其与大麻使用相关性的重要性。主要治疗方式为支持治疗，涵盖物质戒断、辅助患者停止吸食大麻以及临床并发症预防。