Plasmid-mediate Resistance and Virulence of Escherichia coli Strains Isolated from Farm Animals in Russia

Farm animals are a natural reservoir of commensal and pathogenic Escherichia coli strains with high zoonotic potential. Here, we present 5 complete genome sequences of E. coli strains obtained from healthy animals and animals with colisepticemia from industrial and private farms in Russia. We report a wide distribution of virulence-associated (VAGs) and antibiotic-resistance genes (ARGs) in genomes of the sequenced E. coli strains.

农场动物是携带具有高人畜共患病潜力的共生与致病型大肠埃希氏菌（Escherichia coli）菌株的天然贮存宿主。本研究报道了5株大肠埃希氏菌菌株的完整基因组序列，这些菌株分离自俄罗斯工业化养殖场与私人养殖场的健康动物及患大肠杆菌败血症的动物。本研究同时发现，在所测序的大肠埃希氏菌菌株基因组中，毒力相关基因（virulence-associated genes, VAGs）与抗生素抗性基因（antibiotic-resistance genes, ARGs）分布广泛。