Supplemental Table S4
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<b>Supplemental Table 4. </b>Top 10<b> </b>significantly (p<0.05) enriched Ingenuity Canonical Pathways for the 152 transcripts that were differentially expressed in the HFD:control comparison of skeletal muscle transcriptomes but not the HFD+DHA:control comparison (total of 59 enriched pathways), and for the 67 transcripts differentially expressed in the HFD+DHA:control comparison of skeletal muscle transcriptomes, but not the HFD:Control comparison (total of 44 enriched pathways). Transcriptomic analysis was performed on N=4 for each group. Ratio = number of differentially expressed genes/total genes in pathway. Red indicates predicted positive activation of the pathway and upregulation of an individual transcript and blue indicates downregulation.<b></b>
**补充表4**:针对两类差异表达转录本分别富集得到的前10个显著性(p<0.05)Ingenuity经典通路(Ingenuity Canonical Pathways):第一类为152个在高脂饮食(HFD)与对照组的骨骼肌转录组比较中呈差异表达、但在HFD+二十二碳六烯酸(DHA)与对照组的骨骼肌转录组比较中无差异表达的转录本(该类共富集得到59条通路);第二类为67个在HFD+DHA与对照组的骨骼肌转录组比较中呈差异表达、但在HFD与对照组比较中无差异表达的转录本(该类共富集得到44条通路)。本转录组分析每组的样本量为4。富集比值(Ratio)= 差异表达基因数/通路内总基因数。红色代表该通路被预测为正向激活,且对应单个转录本表达上调;蓝色则代表表达下调。
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figshare
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2019-06-27



