Inflammatory markers and biochemical characteristics of type 2 diabetic elderly patients in dependence on elderly or middle age onset of the diagnosis of the diabetes.

a- comparing: depressive syndrome—MCI and depressive syndrome
b- comparing: depressive syndrome—MCI
c- comparing: depressive syndrome—controls
d- comparing: MCI and depressive syndrome—MCI
e- comparing: MCI and depressive syndrome-controls
f- comparing: MCI—controls
DM2—diabetes type 2, OAD- oral anti-diabetic drug, CVD—cardiovascular disease, HA- hypertension, BMI—body mass index, MoCA—Montreal Cognitive Assessment, GDS—Geriatric Depression Scale the Student’s or the Mann Whitney-U tests were used to assess differences between elderly and middle age onset in each group; The ANOVA test followed by post-hoc test was used to test for significant differences between all four groups: first—in elderly onset of diagnosis of diabetes, second—in middle age onset of diagnosis of diabetes.
Inflammatory markers and biochemical characteristics of type 2 diabetic elderly patients in dependence on elderly or middle age onset of the diagnosis of the diabetes.

a. 对比分析：抑郁综合征合并轻度认知障碍（Mild Cognitive Impairment, MCI）与单纯抑郁综合征；
b. 对比分析：抑郁综合征合并轻度认知障碍（Mild Cognitive Impairment, MCI）；
c. 对比分析：抑郁综合征与正常对照组；
d. 对比分析：轻度认知障碍（Mild Cognitive Impairment, MCI）与抑郁综合征合并轻度认知障碍（Mild Cognitive Impairment, MCI）；
e. 对比分析：轻度认知障碍（Mild Cognitive Impairment, MCI）与抑郁综合征-对照组；
f. 对比分析：轻度认知障碍（Mild Cognitive Impairment, MCI）与正常对照组。

术语说明：2型糖尿病（Diabetes Mellitus Type 2, DM2）、口服降糖药（Oral Anti-Diabetic Drug, OAD）、心血管疾病（Cardiovascular Disease, CVD）、高血压（Hypertension, HA）、体质量指数（Body Mass Index, BMI）、蒙特利尔认知评估量表（Montreal Cognitive Assessment, MoCA）、老年抑郁量表（Geriatric Depression Scale, GDS）。

采用Student t检验或Mann-Whitney U秩和检验，评估各组内老年起病与中年起病患者的组间差异；采用单因素方差分析（ANOVA）结合事后检验，对全部4组受试者进行组间显著差异检验，4组分别为老年起病糖尿病诊断组、中年起病糖尿病诊断组。

本研究分析了2型糖尿病老年患者的炎症标志物及生化特征与糖尿病诊断起病年龄（老年起病或中年起病）的相关性。