Additional file 1 of A million-cow genome-wide association study of productive life in U.S. Holstein cows

Additional file 1: Table S1. Top 300 SNP additive effects of PL. This table provides test results for the top 300 additive effects. ‘d’ indicates the SNP is downstream of the gene. ‘u’ indicates the SNP is upstream of the gene. ‘Allele-1’ is the nucleotide of allele ‘1’, and ‘Allele-2’ is the nucleotide of allele ‘2’. ‘al+’ is the positive allele, ‘al–’ is the negative allele, ‘ae+’ is the allelic effect of the positive allele (Eq. (9)), ‘ae–’ is the allelic effect of the negative allele (Eq. (9)). ‘f_al+’ is the frequency of the positive allele. ‘f_al-’ is the frequency of the negative allele. ‘Effect’ is the additive effect of the SNP as the difference between allelic effects of allele ‘1’ and allele ‘2’ (Eq. (10)).

附加文件1：表S1。PL的前300个单核苷酸多态性（Single Nucleotide Polymorphism，SNP）加性效应。本表呈现了排名前300的加性效应检验结果。“d”表示该SNP位于基因下游；“u”表示该SNP位于基因上游。“等位基因1（Allele-1）”为等位基因1的核苷酸，“等位基因2（Allele-2）”为等位基因2的核苷酸。“al+”代表正向等位基因，“al–”代表负向等位基因；“ae+”为正向等位基因的等位基因效应（公式(9)），“ae–”为负向等位基因的等位基因效应（公式(9)）。“f_al+”为正向等位基因的频率，“f_al-”为负向等位基因的频率。“效应（Effect）”为该SNP的加性效应，即等位基因1与等位基因2的等位基因效应之差（公式(10)）。