TaxonomicRestrictedExpressionWindows

Multiple files corresponding to windows with expression above 50 reads in one taxon and absent in all others. Most regions represent only a single taxon, with the exception of those defined for Mus musculus musculus and Mus musculus domesticus populations, in which windows could be present in at least one population, but could also be present in more than one population, provided they would be absent in any other regions. Taxon codes as indicated in the main body of the manuscript. Tissue samples correspond to brain (B), liver (L), and testis (T), and to additional extensive sequencing of brain samples (UDS). Files are in bigWig format, for visualization together with the mm10 version of the mouse reference genome. We provide two IGV (Integrative Genomics Viewer) sessions XML files, which the user can directly load onto the genome browser. One session uses local files, and files have to be present in the same directory as the session file, another makes use of existing files in our local ftp server and does not require the local files, but does require internet connection. In addition to this we provide the expression values supporting the taxonomically-restricted status (*.dat), and a bed file of the relevant regions.

本数据集包含多个文件，对应仅在单个分类单元（taxon）中表达的reads数超过50、且在其余所有分类单元中均无表达的基因组窗口。绝大多数区域仅对应单个分类单元，唯有针对小家鼠指名亚种（Mus musculus musculus）与小家鼠家栖亚种（Mus musculus domesticus）种群定义的区域除外：此类区域的基因组窗口可存在于至少一个种群中，也可存在于多个种群中，但需满足该窗口不会在其他任何区域中出现。分类单元代码详见论文正文。组织样本涵盖脑（B）、肝脏（L）与睾丸（T），另有针对脑样本的深度测序数据集（UDS）。所有文件均采用bigWig格式，可配合小鼠参考基因组mm10版本用于可视化分析。本次提供两份IGV（Integrative Genomics Viewer，整合基因组浏览器）会话XML文件，用户可直接将其加载至基因组浏览器中：其中一份会话使用本地文件，需将相关文件与会话文件置于同一目录下；另一份会话则调用本地FTP服务器上的已有文件，无需本地文件，但需联网访问。此外，我们还提供了支持该分类单元限制性表达特征的表达量数据（*.dat格式），以及对应目标区域的BED格式文件。