PsPM-FSS7B: Inhibiting human aversive memory by transcranial theta-burst stimulation to primary sensory cortex

This dataset includes skin conductance response (SCR), electromygoram (EMG), and pupil size response (PSR) measurements. Also included are CS and US information, keypress responses, keypress response times and key correctness. The dataset contains data from 68 healthy unmedicated participants (34 females) participating in a classical (Pavlovian) discriminant delay fear conditioning task. Simple and complex CS are deliverd to the intermediate phalanges of the index and middle fingers of the nondominant hand. Simple stimulis are stimulations to either index or middle finger, complex stimulis are stimulations of different temporal structure to both index and middle fingers. CS intensity is set to a perceivable but not unpleasant level. US is a train of electric square pulses delivered with a constant current stimulator (Digitimer DS7A, Digitimer, Welwyn Garden City, UK) on participants' dominant forearm through a pin-cathode/ring-anode configuration. SOA betwen the CS and US is 3.5 s. The ITI is randomly determined on each trial to be 7, 9, or 11 s. The study included fear acquisition (day 1), recall and retest sessions (day 2). Participants are divided into experimental and control groups, where experimental group received continuous theta-burst stimulation on primary somatosensory cortex contralateral to the CS hand immediately prior to fear acquisition, and control group received the same stimulation to the primary somatosensory cortex ipsilateral to the CS hand. For SCR data from the acquisition session, there are 62 datasets (28 experimental, 34 control), and for PSR, 37 datasets (20 experimental, 17 control). For EMG data from the recall session, there are 52 datasets (25 experimental, 27 control). For SCR data from the retest session, there are 56 datasets (27 experimental, 39 control), and for PSR, 42 datasets (22 experimental, 20 control).

本数据集包含皮肤电反应（skin conductance response, SCR）、肌电图（electromyogram, EMG）以及瞳孔大小反应（pupil size response, PSR）的测量数据，同时涵盖条件刺激（CS）与非条件刺激（US）相关信息、按键反应、按键反应时及按键正确性数据。本数据集的数据来自68名未服用药物的健康被试（其中女性34名），所有被试均参与了一项经典（巴甫洛夫）判别式延迟恐惧条件化任务。
简单与复杂条件刺激均施加于非利手的示指与中指的指骨中段：简单刺激为单独施加于示指或中指的刺激，复杂刺激为同时施加于示指与中指且具有不同时间结构的刺激。条件刺激的强度设置为可被感知但不会引起不适的水平。
非条件刺激为由恒流刺激器（Digitimer DS7A, Digitimer, 英国韦林花园城）产生的方形电脉冲串，通过针状阴极-环状阳极配置施加于被试利手侧的前臂。条件刺激与非条件刺激的刺激呈现异步间隔（stimulus onset asynchrony, SOA）为3.5秒。每一试次的试间间隔（inter-trial interval, ITI）随机设置为7秒、9秒或11秒。
本研究包含恐惧习得阶段（第1天）、回忆与重测阶段（第2天）。被试被分为实验组与对照组：实验组在恐惧习得开始前即刻，接受施加于与条件刺激刺激手对侧的初级躯体感觉皮层的持续性θ爆发刺激；对照组则接受施加于与条件刺激刺激手同侧的初级躯体感觉皮层的同等刺激。
针对习得阶段的皮肤电反应数据，共包含62份数据集（实验组28份、对照组34份）；针对瞳孔大小反应数据，共包含37份数据集（实验组20份、对照组17份）。针对回忆阶段的肌电图数据，共包含52份数据集（实验组25份、对照组27份）。针对重测阶段的皮肤电反应数据，共包含56份数据集（实验组27份、对照组39份）；针对瞳孔大小反应数据，共包含42份数据集（实验组22份、对照组20份）。