Summary of sequence processing.

$Sample abbreviations: Co, control group; Ex, experimental group; pre, before intervention; post, after intervention.*Number of remaining reads after applying quality criteria as described in the Methods section.**Unique high quality reads after de-noising the data by Single Linkage Preclustering at 2% edit distance.

样本缩写定义如下：Co为对照组（control group），Ex为实验组（experimental group）；pre指代干预前，post指代干预后。
* 按方法部分所述质量标准筛选后剩余的读段（reads）数量。
** 经2%编辑距离下的单链接预聚类（Single Linkage Preclustering）对数据进行降噪处理后得到的唯一高质量读段。