Chemical Inhibition of Salt-Inducible Kinase as Therapeutic Strategy in Acute Myeloid Leukemia [ChIP-Seq]. Chemical Inhibition of Salt-Inducible Kinase as Therapeutic Strategy in Acute Myeloid Leukemia [ChIP-Seq]

Genome-wide binding/occupancy profiling by high throughput sequencing Overall design: Genome-wide analysis of H3K27ac modification in AML with SIK inhibitor treatment

基于高通量测序的全基因组结合/占用谱分析
实验设计：对经盐诱导激酶（Salt-Inducible Kinase, SIK）抑制剂处理的急性髓系白血病（Acute Myeloid Leukemia, AML）样本，开展组蛋白H3第27位赖氨酸乙酰化修饰（H3K27ac）的全基因组分析。