RNA-seq performed on FFPE sarcoma blocks

We validated the technological and material transfers of the CINSARC signature. We performed both microarray and RNA-seq analysis and compared prognostic values based on the CINSARC classification. We measure significant metastasis-free survivals with both approaches. Additionally, depending on RNA degradation, transcriptomic analysis from FFPE blocks show similar CINSARC classification.

我们验证了CINSARC特征（CINSARC signature）的技术与材料转移性。本研究同时开展了基因芯片（microarray）与RNA测序（RNA-seq）分析，并基于CINSARC分类比较了二者的预后价值。两种分析方法均观测到具有统计学意义的无转移生存期。此外，即便存在RNA降解情况，来自福尔马林固定石蜡包埋（FFPE）组织块的转录组分析仍可获得一致的CINSARC分类结果。