Result of fluorescence-based NA inhibition assay.

Figshare2018-11-15 更新2026-04-29 收录

抗流感病毒药物筛选

神经氨酸酶活性测定

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Result of fluorescence-based NA inhibition assay.

基于荧光的NA（Neuraminidase）抑制试验结果

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2018-11-15

Akt inhibitor MK2206 prevents influenza A(H1N1)pdm09 virus infection in vitro. Homo sapiens

抗流感病毒药物筛选

Akt抑制剂抗病毒机制

The influenza A(H1N1)pdm09 virus caused a global flu pandemic in 2009 and contributes to seasonal epidemics. Different treatment and prevention options for influenza have been developed and applied wi

NIAID Data Ecosystem60

Treatment with the NR4A1 agonist cytosporone B controls influenza virus infection and improves pulmonary function in infected mice

抗流感病毒药物筛选

先天免疫调控

The transcription factor NR4A1 has emerged as a pivotal regulator of the inflammatory response and immune homeostasis. Although contribution of NR4A1 in the innate immune response has been demonstrate

NIAID Data Ecosystem30

Raw data and data accompanying publication: https://doi.org/10.1371/journal.pone.0335975

RNAG-四链体药物靶点

抗流感病毒药物筛选

The influenza virus is an interesting research subject due to its serious threat to global public health. To date, various structural motifs from the influenza A virus (IAV) genome have been studied.

Zenodo2026-02-24 更新20

Enzyme kinetics of 245 NA Gly- and 245 NA Gly+ viruses.

病毒酶学

神经氨酸酶活性测定

NA-Flour assay conducted in triplicate, representative results shown of two biological replicates. Values calculated with Graph Pad prism 8 with Michaelis-Menten non-linear regression. 95% confidence

NIAID Data Ecosystem40

Neuraminidase enzyme kinetics parameters of influenza viruses.

流感病毒传播动力学

神经氨酸酶活性测定

aVirus infectivity was determined by plaque assay in MDCK cells. Values are expressed in log10 PFU/mL (mean ± SD) from 3 independent determinations. bResults represent the means ± SD from 7 independen

NIAID Data Ecosystem20

Result of fluorescence-based NA inhibition assay.

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