Crystal structure of human acetylcholinesterase in complex with ((6-((2E,4E)-5-(benzo[d][1,3]dioxol-5-yl)penta-2,4-dienamido)hexyl)triphenylphosphonium bromide)

Crystal structure of human acetylcholinesterase in complex with ((6-((2E,4E)-5-(benzo[d][1,3]dioxol-5-yl)penta-2,4-dienamido)hexyl)triphenylphosphonium bromide) Descriptor: (2~{E},4~{E})-5-(1,3-benzodioxol-5-yl)-~{N}-[6-(triphenyl-$l^{5}-phosphanyl)hexyl]penta-2,4-dienamide, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... Authors: Da Silva, O, Dias, J, Nachon, F, Brazzolotto, X. Deposit date: 2020-07-28 Release date: 2021-06-09 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (3 Å) Cite: Fine-Tuning the Biological Profile of Multitarget Mitochondriotropic Antioxidants for Neurodegenerative Diseases. Antioxidants (Basel), 10, 2021

人类乙酰胆碱酯酶（acetylcholinesterase）与((6-((2E,4E)-5-(苯并[d][1,3]二氧杂环戊烯-5-基)戊-2,4-二烯酰胺基)己基)三苯基溴化鏻)复合物的晶体结构。描述项：(2E,4E)-5-(1,3-苯并二氧杂环戊烯-5-基)-N-[6-(三苯基-λ⁵-膦烷基)己基]戊-2,4-二烯酰胺、2-乙酰氨基-2-脱氧-β-D-吡喃葡萄糖、2-乙酰氨基-2-脱氧-β-D-吡喃葡萄糖-(1→3)-2-乙酰氨基-2-脱氧-β-D-吡喃葡萄糖…… 作者：Da Silva O、Dias J、Nachon F、Brazzolotto X。沉积日期：2020年7月28日；发布日期：2021年6月9日；最后修改日期：2024年10月16日。实验方法：X射线衍射（X-RAY DIFFRACTION，分辨率3 Å）。引用文献：《Fine-Tuning the Biological Profile of Multitarget Mitochondriotropic Antioxidants for Neurodegenerative Diseases》，发表于*Antioxidants (Basel)*，第10卷，2021年。