Function of human SIRPa low and SIRPa high macrophages in Mycobacterium tuberculosis infection

to induce and sort human SIRPa low and SIRPa high macrophages from PBMCs, and then cultured them under tuberculosis challengement. And then determine their global transcripts differences between the SIRPa low and SIRPa high group.

本数据集的实验流程为：从外周血单个核细胞（PBMCs）中诱导并分选人SIRPa低表达和高表达巨噬细胞，随后将两组细胞置于结核感染刺激条件下培养，进而检测SIRPa低表达组与高表达组之间的全局转录组差异。