Gene database for Bacillus cereus ATCC 14579

Facultative anaerobic, Gram-positive and rod-shaped, Bacillus cereus is a common bacterium that we encounter during episodes of food poisoning. The bacterium is a common inhabitant of soil and water. From a food safety perspective, B. cereus is a serious microbial threat given its ability to form endospore, which makes its eradication during food processing a top priority. Besides sporulation ability, B. cereus also packs another microbial weapon, cereolysin, which is a virulence factor important to pathogenesis. This work sought to illuminate the genetic repertoire of this important food pathogen by parsing the annotated genome sequence of B. cereus ATCC 14579 obtained from Genbank. Comprising gene name, gene function and gene sequence of all genes in the genome of B. cereus, the resource should be useful in molecular cloning work or genome editing research seeking to understand the functions of individual genes in this important endospore forming pathogen.

兼性厌氧、革兰氏阳性、杆状的蜡样芽孢杆菌（Bacillus cereus）是引发食物中毒的常见致病菌，同时也是土壤与水环境中的常见定植微生物。从食品安全视角来看，蜡样芽孢杆菌是一类极具威胁的微生物病原，因其具备形成内生芽孢的能力，使得食品加工过程中对其的彻底灭杀成为首要防控任务。除内生芽孢形成能力外，蜡样芽孢杆菌还携带另一毒力因子——蜡溶素（cereolysin），该因子是其致病过程中的关键毒力因素。本研究通过解析从GenBank获取的蜡样芽孢杆菌ATCC 14579的注释基因组序列，旨在阐明这一重要食源性致病菌的完整遗传组成。该数据集涵盖蜡样芽孢杆菌全基因组中所有基因的名称、功能及序列信息，可用于旨在解析该重要芽孢形成致病菌单个基因功能的分子克隆研究或基因组编辑相关研究。