Comparison of gene expression profiles between paired primary and metastasis colorectal carcinoma

Paired tissues (normal colon, primary colorectal carcinoma, normal liver, liver metastasis of colorectal carcinoma) from 2 colorectal carcinoma patients in Taiwan were processed to generate total RNA, which was subsequently analyzed for gene expression using Affymetrix U133 plus 2.0 arrays. Comparison of gene expression profiles between paired normal colon and primary colorectal carcinoma; between primary colorectal carcinoma and liver metastasis colorectal carcinoma

本研究针对中国台湾地区2名结直肠癌患者的配对组织样本（正常结肠组织、原发性结直肠癌组织、正常肝脏组织、结直肠癌肝转移组织）进行处理以提取总RNA，随后采用Affymetrix U133 Plus 2.0基因芯片开展基因表达分析，并对比了配对正常结肠组织与原发性结直肠癌组织、以及原发性结直肠癌组织与结直肠癌肝转移组织的基因表达谱。