A partnership between the lipid scramblase XK and the lipid transfer protein VPS13A at the plasma membrane

This upload contains files documented in a preprint and a publication. Preprint: https://doi.org/10.1101/2022.03.30.486314 Publication: https://doi.org/10.1073/pnas.2205425119 The files uploaded here are: - Alphafold predictions for VPS13A N-term (a.a. 1-2100) and C-term (a.a. 1021-3174). The .pse file is the pymol structure alignment of the two predicted VPS13A portions, join at aminoacid position D14 with the different representations presented throughout the paper stored as pymol "scenes". - AlphaFold-Multimer prediction for the interaction between XK and the C-term region of VPS13A is also included. - An excel file containing the tabular data for the graphs in Figures 1G, S2E and 4D.本上传数据集对应一篇预印本与一篇正式发表的学术论文，相关链接如下： 预印本：https://doi.org/10.1101/2022.03.30.486314；正式发表论文：https://doi.org/10.1073/pnas.2205425119。 本次上传的文件具体如下： - VPS13A蛋白N端（氨基酸残基1-2100）与C端（氨基酸残基1021-3174）的阿尔法折叠（AlphaFold）预测结构。其中.pse格式文件为PyMOL分子可视化软件（PyMOL）结构对齐文件，将两个预测得到的VPS13A片段在氨基酸位点D14处拼接，并将论文中呈现的多种不同展示形式以PyMOL“场景”的形式存储。 - 包含XK蛋白与VPS13A C端区域相互作用的阿尔法折叠-多聚体（AlphaFold-Multimer）预测结果。 - 一份Excel格式文件，其中存储了图1G、补充图S2E与图4D中对应图表的制表原始数据。