Additional file 1: of Red blood cell indices and anaemia as causative factors for cognitive function deficits and for Alzheimer’s disease

Table S1. Sample set description. Table S2. MR replication in release 2 of the UK Biobank data. Table S3. MR results for RET trait. Table S4. General linear model results show an association between AD patients and red blood indices in UK Biobank. Table S5. Significantly enriched KEGG pathways for MCH decline correlated genes. (XLSX 18 kb)

附表S1：样本集描述。
附表S2：英国生物样本库（UK Biobank）第二版数据中的孟德尔随机化（Mendelian Randomization，MR）验证结果。
附表S3：RET特征的孟德尔随机化（MR）分析结果。
附表S4：一般线性模型分析结果显示，英国生物样本库内阿尔茨海默病（Alzheimer's Disease，AD）患者与红细胞参数间存在关联。
附表S5：与平均红细胞血红蛋白含量（Mean Corpuscular Hemoglobin，MCH）降低相关基因的显著富集京都基因与基因组百科全书（Kyoto Encyclopedia of Genes and Genomes，KEGG）通路。（XLSX格式，大小18 KB）