Sample characteristics.

Sample size (N), mean and standard deviation for age in years, Clinical Dementia Ratings (CDR), the percentage of females in the sample (%female), percentage of the sample that carries at least one APOE ε4 allele (%ε4pos) and the mean and standard deviation for Aβ42 in pg/ml and ptau181 in pg/ml for the complete Washington University CSF sample (WU: All), cases and controls and the complete Alzheimer's Disease Neuroimaging Initiative (ADNI: All), cases and controls are shown.1analyzed with Innotest ELISA (Innogenetics, Ghent, Belgium).2analyzed with AlzBia3 (xMAP) assay (Innogenetics, Ghent, Belgium).

本数据集展示了完整华盛顿大学脑脊液（CSF, Cerebrospinal Fluid）样本（WU: All）及其病例组、对照组，以及完整阿尔茨海默病神经影像倡议（ADNI, Alzheimer's Disease Neuroimaging Initiative）样本（ADNI: All）及其病例组、对照组的如下统计指标：样本量（N）、年龄（单位：年）的均值与标准差、临床痴呆评定量表（CDR, Clinical Dementia Ratings）得分、样本女性占比（%female）、携带至少1个载脂蛋白E ε4（APOE ε4）等位基因的样本占比（%ε4pos），以及β淀粉样蛋白42（Aβ42）与磷酸化tau181（ptau181，单位均为pg/ml）的均值与标准差。其中，1. 采用比利时根特英诺维特（Innogenetics）公司的Innotest酶联免疫吸附测定（ELISA）完成检测；2. 采用比利时根特英诺维特（Innogenetics）公司的AlzBia3（xMAP）检测法完成检测。