Example outputs from the meta-analysis fine-mapping simulation pipeline

This dataset contains example outputs from the meta-analysis fine-mapping simulation pipeline (https://github.com/mkanai/meta-finemapping-simulation) used in Kanai, M. et al. (2022). Due to a storage limit, only example outputs have been deposited. Each directory contains the following simulated files. hapgen2_genotypes: This directory contains simulated genotypes from HAPGEN2, restricted to each genotyping array as described in the manuscript. assoc: This directory contains simulated GWAS results from PLINK2. Due to a storage limit, only one simulated phenotype is included. meta_analysis and meta_analysis_grch38: This directory contains meta-analysis results across all the meta-analysis configurations (Table S4, ST4_simulation_configurations.tsv). Due to a storage limit, only one simulated phenotype is included. Directories are separated by whether variants are on GRCh37 or GRCh38.

本数据集包含Kanai等（2022）研究中使用的meta分析精细定位模拟流程（https://github.com/mkanai/meta-finemapping-simulation）的示例输出结果。受存储容量限制，仅存档了示例输出。每个目录包含以下模拟文件：
hapgen2_genotypes：该目录存储来自HAPGEN2的模拟基因型数据，限定为论文中描述的各基因分型阵列对应的数据集。
assoc：该目录存储来自PLINK2的模拟全基因组关联研究（Genome-Wide Association Study, GWAS）结果。受存储容量限制，仅包含一个模拟表型的数据。
meta_analysis与meta_analysis_grch38：该组目录存储所有meta分析配置下的meta分析结果（详见表S4，ST4_simulation_configurations.tsv）。受存储容量限制，仅包含一个模拟表型的数据。目录依据变异所属的参考基因组版本（GRCh37或GRCh38）进行划分。