tRNA-Guanine Transglycosylase (TGT) in Complex with 2-{[2-(Morpholin-4-yl)ethyl]amino}-1H,7H,8H-imidazo[4,5-g]quinazolin-8-one
收藏Protein Data Bank Japan2023-09-20 更新2026-03-21 收录
下载链接：
https://pdbj.org/mine/summary/4q4r
下载链接
链接失效反馈官方服务：
资源简介：
tRNA-Guanine Transglycosylase (TGT) in Complex with 2-{[2-(Morpholin-4-yl)ethyl]amino}-1H,7H,8H-imidazo[4,5-g]quinazolin-8-one Descriptor: 2-{[2-(4-Morpholinyl)ethyl]amino}-1,7-dihydro-8H-imidazo[4,5-g]quinazolin-8-one, GLYCEROL, Queuine tRNA-ribosyltransferase, ... Authors: Neeb, M, Heine, A, Klebe, G. Deposit date: 2014-04-15 Release date: 2014-07-09 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.448 Å) Cite: Beyond Affinity: Enthalpy-Entropy Factorization Unravels Complexity of a Flat Structure-Activity Relationship for Inhibition of a tRNA-Modifying Enzyme. J.Med.Chem., 57, 2014
tRNA-鸟嘌呤转糖基酶（tRNA-Guanine Transglycosylase, TGT）与2-{[2-(4-吗啉基)乙基]氨基}-1H,7H,8H-咪唑并[4,5-g]喹唑啉-8-酮的复合物
描述：2-{[2-(4-吗啉基)乙基]氨基}-1,7-二氢-8H-咪唑并[4,5-g]喹唑啉-8-酮、甘油、tRNA-鸟嘌呤转糖基酶（Queuine tRNA-ribosyltransferase）……
作者：M·尼布、A·海涅、G·克莱贝
提交日期：2014-04-15
发布日期：2014-07-09
最后修改日期：2023-09-20
实验方法：X射线衍射（1.448埃）
引用：《超越亲和力：焓-熵分解揭示tRNA修饰酶抑制剂的平面构效关系复杂性》，《药物化学杂志（J. Med. Chem.）》，第57卷，2014年
创建时间：
2014-04-15
