Genotyping results for RNF34 and KDM2B mutations.

aCattle recorded as parent of affected calves.bFor this cow only one single suspicious offspring was recorded by the breeding organization and the diagnosis of this calf had not been confirmed by necropsy. Genotyping of additional flanking markers revealed that this animal did not carry the disease-associated haplotype. Therefore, the reported calf most likely represented a phenocopy and the parent is indeed free of the deleterious mutation.

a. 被记录为患病犊牛亲本的牛只。
b. 针对该头牛，育种机构仅记录了1头疑似患病后代，且该犊牛的诊断尚未经剖检（necropsy）确认。通过对其侧翼附加标记开展基因分型（genotyping），发现该个体未携带疾病相关单倍型（haplotype）。因此，本次报道的犊牛极大概率为拟表型（phenocopy），而该亲本确实未携带该有害突变（deleterious mutation）。