Prevalence and factors associated with acute kidney injury in patients in intensive care units

ABSTRACT Objectives: to identify the prevalence and factors associated with the development of acute kidney injury in critically ill patients. Methods: a cross-sectional study, conducted from June 2018 to August 2019. The Kidney Disease Improving Global Outcomes was used to classify acute kidney injury. A significant value was set at p 1.5 mg/dL, also, when applied logistic regression, were 7 times more likely to develop acute kidney injury, Odds Ratio 7.018. More than half (56.6%) of the patients with acute kidney injury died. Moreover, 26.7% of these patients developed pressure sore. Conclusions: the prevalence of kidney injury was high (35.8%). The patients who developed it had a higher severity, mortality, and pressure sore index.

摘要
研究目的：明确重症患者急性肾损伤（acute kidney injury）的患病率及其相关发病危险因素。
研究方法：本研究为横断面研究，于2018年6月至2019年8月期间开展。采用改善全球肾脏病预后组织（Kidney Disease Improving Global Outcomes）制定的标准对急性肾损伤进行分级。本研究设定检验临界值为1.5mg/dL；经logistic回归分析显示，相关患者发生急性肾损伤的风险较对照组提升7倍，优势比（Odds Ratio）为7.018。合并急性肾损伤的患者中，超过半数（56.6%）发生死亡。此外，该类患者中有26.7%并发压疮。
研究结论：急性肾损伤的患病率较高（35.8%）。发生急性肾损伤的患者病情严重程度更高，死亡率及压疮发生率亦显著升高。