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<strong>This dataset is part of the manuscript: "<em>Systematic review of the Cerrado Pé-de-Gigante flora, one of the largest protected Cerrado fragments in São Paulo state, Brazil</em>".</strong><br> <br> The Cerrado Pé-de-Gigante is located in the State of São Paulo, southeastern Brazil, and it comprises a part of the Vassununga State Park, a integral protection conservation unit. This study presents an updated list of the flora of Cerrado Pé-de-Gigante which was developed through a systematic search in the literature, consultations to virtual herbaria, and field validation. In the state of São Paulo, the original vegetation of the remaining Cerrado is mostly in small fragments and in areas not properly protected. In this regard, we emphasize the relevance in the context of conservation of biodiversity as a whole of Cerrado Pé-de-Gigante, since our results pointed to the record of 681 plant species for this area of just over 1200 ha. The final list includes angiosperms, ferns and bryophytes and their respective conservation status, habit and herbarium deposit vouchers. <pre> </pre><strong>本数据集隶属于学术论文手稿：<em>《巴西圣保罗州最大的受保护塞拉多（Cerrado）片段之一——佩-德-吉甘特塞拉多（Cerrado Pé-de-Gigante）植物区系系统综述》</em>。</strong><br><br>佩-德-吉甘特塞拉多位于巴西东南部圣保罗州境内，隶属于瓦苏农加州立公园（Vassununga State Park）这一严格保护型保护地。本研究通过系统文献检索、虚拟标本馆咨询与野外验证工作，编制了佩-德-吉甘特塞拉多植物区系的最新名录。在圣保罗州境内，现存塞拉多原生植被多为小型片段，且大多未得到妥善保护。有鉴于此，本研究着重强调佩-德-吉甘特塞拉多对于整体生物多样性保护的重要意义：本次调查在这片面积仅1200余公顷的区域内记录到681种植物。最终名录涵盖被子植物、蕨类植物与苔藓植物，同时包含各物种的保护等级、生长型及标本馆藏凭证信息。<pre> </pre>