Dataset 1. Information on the 276 SNPs genotyped in 177 genes in P. falciparum parasite populations from The Gambia, Kilifi and Rachuonyo South

Dataset 1: Information on the 276 SNPs genotyped in
177 genes in P. falciparum parasite
populations from The Gambia, Kilifi and Rachuonyo South. The columns
contain the following information: study_location, site of sample collection;
sample_id, unique sample identifier; gene_symbol, gene name (if available);
chr_valid, chromosome; coord_valid= base position of SNP on chromosome;
sequence_code, SNP name; assay_code, name of assay; rsnumber, unique SNP
identifier in dbSNP; reference_allele, 3D7 reference allele,
alternative_allele, alternative allele; single letter code, IUPAC code for
SNPs; result, genotype call after processing; allele1, IUPAC code for allele 1;
allele2, IUPAC code for allele 2; allele_ratio1, proportion of allele 1;
allele_ratio2, proportion of allele 2; pass_fail, coding of SNP based on
availability of valid genotype (pass) or lack of a valid genotype (fail).
Geospatial data for homestead location is considered sensitive data and
therefore cannot be made open access. However, it can be accessed through a
request to our data governance committee, using the email address
mmunene@uat/newsite.

数据集1：涵盖来自冈比亚、基利菲及拉乔尼奥南地区的恶性疟原虫（*Plasmodium falciparum*，简称P. falciparum）种群中177个基因的276个单核苷酸多态性（Single Nucleotide Polymorphism, SNP）分型信息。各列对应的字段说明如下：study_location为研究地点，即样本采集位点；sample_id为唯一样本标识符；gene_symbol为基因符号（若可获取）；chr_valid为染色体编号；coord_valid为SNP在染色体上的碱基位置；sequence_code为SNP名称；assay_code为检测试验名称；rsnumber为dbSNP数据库中该SNP的唯一标识符；reference_allele为3D7参考株的参考等位基因；alternative_allele为替代等位基因；single letter code为SNP的国际纯粹与应用化学联合会（IUPAC）单字母编码；result为经过后续处理后的基因型分型结果；allele1为等位基因1的IUPAC编码；allele2为等位基因2的IUPAC编码；allele_ratio1为等位基因1的占比；allele_ratio2为等位基因2的占比；pass_fail为基于有效基因型是否可获得的SNP质控标记，其中pass表示存在有效基因型（合格），fail表示无有效基因型。宅基地位置的地理空间数据属于敏感数据，因此无法公开获取。但研究者可通过向数据治理委员会发送邮件至mmunene@uat/newsite申请访问该数据。