Hematological profile of captive bearded capuchin monkeys (Sapajus libidinosus) from Northeastern Brazil

ABSTRACT: Bearded Capuchin or Black-striped Capuchin monkeys (Sapajus lidibinosus) are New World robust capuchin monkeys widely used in medical research. Few data are available concerning hematological reference values for these species, with no studies available from the Northeast region in Brazil. The aim of this study was to determine the hematological reference values for healthy bearded capuchin monkeys and to analyze the influence of sex and age factors. Blood samples were collected from 50 healthy bearded capuchin monkeys housed in captivity. These were analysed for total erythrocyte, hemoglobin, leukocyte and platelet count, packed cell volume (PCV), mean corpuscular volume (MCV), mean corpuscular hemoglobin (MCH) and mean corpuscular hemoglobin concentration (MCHC). When considering the age factor, significant differences were reported for total erythrocyte count, PCV, hemoglobin, total leucocytes, band neutrophils, eosinophils and lymphocytes (higher in juveniles). Significant sex-associated differences were noted for total erythrocyte count, PCV, hemoglobin (higher in males) and number of lymphocytes (higher in females).We have reported for the first time the hematological profile of bearded capuchin monkeys in captivity in the state of Paraíba, Brazil. These results can contribute for a better understanding of the normal physiology of capuchin monkeys, while demonstrating that factors such as sex and age influence hematological parameters should be taken into consideration in the hematological evaluation of this species.

摘要：髭僧帽猴（又称黑纹僧帽猴，学名Sapajus lidibinosus）属于新世界粗壮僧帽猴，被广泛应用于医学研究领域。目前关于该物种的血液学参考值数据较为匮乏，且巴西东北部地区暂无相关研究报道。本研究旨在测定健康髭僧帽猴的血液学参考值，并分析性别与年龄因素对其的影响。本研究采集了50只圈养健康髭僧帽猴的血液样本，对其红细胞总数、血红蛋白、白细胞及血小板计数，红细胞比容（packed cell volume, PCV）、平均红细胞体积（mean corpuscular volume, MCV）、平均红细胞血红蛋白量（mean corpuscular hemoglobin, MCH）与平均红细胞血红蛋白浓度（mean corpuscular hemoglobin concentration, MCHC）进行了检测分析。按年龄因素分析时，研究发现红细胞总数、PCV、血红蛋白、白细胞总数、杆状核中性粒细胞、嗜酸性粒细胞及淋巴细胞计数存在显著差异（幼体组各项指标水平更高）。按性别因素分析时，红细胞总数、PCV、血红蛋白（雄性组水平更高）以及淋巴细胞计数（雌性组水平更高）存在显著差异。本研究首次报道了巴西帕拉伊巴州圈养髭僧帽猴的血液学特征。本研究结果有助于更深入地了解僧帽猴的正常生理机能，同时表明在该物种的血液学评估中，应将性别与年龄等影响血液学参数的因素纳入考量范围。