Predictive values for changes of markers.

WBC = white blood cell count; CRP = C-reactive protein; PCT = procalcitonin; AUROC = area under the receiver operating characteristic curve; Sens = sensitivity; Spec = specificity at optimal cut off values. PPV = positive predictive value; NPV = negative predictive value. Statistically significant AUROC’s are given only. A value less than 1 denotes a fractional decrease from Day 0–2 to 7 and a value above 1 a fractional increase.

本研究涉及的指标定义如下：白细胞计数（white blood cell count, WBC）、C反应蛋白（C-reactive protein, CRP）、降钙素原（procalcitonin, PCT）、受试者工作特征曲线下面积（area under the receiver operating characteristic curve, AUROC）、灵敏度（sensitivity, Sens）、最佳截断值下的特异度（specificity at optimal cut-off values, Spec）、阳性预测值（positive predictive value, PPV）及阴性预测值（negative predictive value, NPV）。仅保留具有统计学显著性的AUROC值。若数值小于1，则代表第0~2天至第7天发生分数级降低；若数值大于1，则代表发生分数级升高。