CS Home Training data.xlsx

After baseline measurements in-lab, participants were sent home to train for several months (subacute (SA): 4.9±0.6 months [mean ± SD]; chronic (CH): 6.8±4.0 months). They used their personal computers with a chin/forehead-rest provided by the lab, which they were instructed to position 42cm away from their display during training. Participants performed 300 trials of their assigned training tasks (Static, Motion or Flicker) per location per day, at least five days per week, and they emailed their data log files back to the lab for analysis every week. During home training sessions, they were instructed to stay fixated on the fixation spot and warned that inadequate fixation accuracy could limit recovery.Session thresholds were calculated by fitting a Weibull function with a 72.5 percent correct performance threshold criterion. After participants’ thresholds improved consistently for at least 20 sessions, we moved their training stimulus 1˚ deeper into the blind field along the x-axis (Cartesian coordinate space). Because the diameter of the stimulus is 2.5 ˚, the new training location had ~80% overlap with the original training location. Once participants trained for about 4 months, with at least one improved location (defined as consistently good contrast thresholds at that location), they were brought back to the lab, and performance at all home-trained locations was verified with eye tracker-enforced fixation control. We aimed for a similar number of training sessions at the blind-field locations of interest before scheduling people to return for in-lab performance verification. However, the amount of time elapsed until the return visit did vary, as it was affected by the individual’s rate of improvement, their work/family schedules, and ability to travel to our single study site (participants originated from across the entire United States and Canada). All participants were best corrected using glasses or contact lenses during testing and training. The Research Subjects Review Board approved study procedures at the University of Rochester, which were conducted as per the Declaration of Helsinki, with written informed consent obtained from each participant, and participation was voluntary.

在实验室完成基线测量后，受试者被带回家进行数月训练：亚急性（subacute, SA）组训练时长为4.9±0.6个月（均值±标准差（standard deviation, SD）），慢性（chronic, CH）组为6.8±4.0个月。训练期间，受试者使用实验室提供的带下颌/额头支撑托架的个人电脑，并需将设备调整至距离显示器42厘米的位置。受试者每日需针对每个训练位置完成300次指定训练任务（静态、运动或闪烁范式），每周至少训练5天，并每周通过电子邮件将数据日志文件发送至实验室以供分析。居家训练过程中，受试者需始终注视注视点，同时被告知若注视精度不足可能会限制康复效果。会话阈值通过拟合威布尔函数（Weibull function）计算得到，性能阈值判定标准为正确率72.5%。当受试者的阈值连续至少20个会话均出现改善后，我们将其训练刺激沿笛卡尔坐标系（Cartesian coordinate space）的x轴方向向视野盲区推进1°。由于刺激直径为2.5°，新训练位置与原训练位置的重叠度约为80%。当受试者完成约4个月训练，且至少有一个训练位置的阈值得到持续改善（定义为该位置的对比阈值始终处于良好水平）后，我们将其召回实验室，通过眼动仪强制注视控制来验证其在所有居家训练位置的表现。在安排受试者返回实验室进行表现验证前，我们计划让其在目标视野盲区位置完成相近数量的训练会话。但受试者的返回间隔存在差异，这受到个体改善速度、工作/家庭日程以及前往我们唯一研究站点的出行能力影响（受试者来自美国及加拿大全境）。所有受试者在测试与训练期间均佩戴眼镜或隐形眼镜以获得最佳矫正视力。本研究流程已通过罗切斯特大学（University of Rochester）研究受试者审查委员会的批准，所有实验均遵循《赫尔辛基宣言》（Declaration of Helsinki）开展，每位受试者均已签署书面知情同意书，且参与本研究完全自愿。