Mycobacterium tuberculosis RefSeq Genome. Mycobacterium tuberculosis

Bacterial plasmids are self-replicating, extrachromosomal elements associated with a variety of phenotypic traits including virulence, enhanced fitness, and resistance to antimicrobial agents. They play an important role in the transfer of genetic material in microbial populations within and between the species. The study of mobile genetic elements such as plasmids is of particular interest because of their ecological, biological, and clinical significance. The Refseq collection of plasmids represent complete sequences derived from different bacterial strains and is organized by host organism at the species level.

细菌质粒（bacterial plasmids）是一类可自我复制的染色体外遗传因子，与多种表型性状相关，包括毒力、适应性增强以及抗微生物药物耐药性。其在微生物种群内部及跨物种间的遗传物质传递过程中发挥关键作用。鉴于移动遗传元件（mobile genetic elements）在生态、生物学及临床领域的重要意义，针对质粒这类移动遗传元件的研究备受关注。RefSeq质粒集包含源自不同细菌菌株的完整序列，并按照宿主物种进行分类整理。