Omics-Lethal Human Viruses, West Nile Experiment WGCN002

The purpose of this experiment was to evaluate the host response to wild-type West Nile virus infectious clone (WNV-NY99 clone 382) and mutant (WNVE218A) virus infection. Sample data was obtained from mouse granule cell neurons for mRNA and miRNA expression analysis. See Experiment WGCN003 for corresponding independent biological replicate study. Secondary host-associated viral dataset downloads contain one or more statistically processed (normalization data transformation) quantitative dataset collections resulting in qualitative expression analyses of primary host-pathogen experimental study designs. Transcriptomics dataset downloads have a direct relationship to a primary sample submission corresponding to a specific West Nile virus infection.

本实验旨在评估宿主对野生型西尼罗河病毒（West Nile virus）感染性克隆（WNV-NY99 clone 382）及突变体（WNVE218A）病毒感染的应答反应。实验样本采集自小鼠颗粒细胞神经元，用于mRNA与miRNA的表达分析。相关独立生物学重复研究详见实验WGCN003。宿主相关病毒二级数据集下载项包含经统计学处理（含数据标准化与转换）的定量数据集合集，可用于对原代宿主-病原体实验研究设计开展定性表达分析。转录组数据集下载项与对应特定西尼罗河病毒感染的原代样本提交直接相关。