Effect of fasting on the mRNA of the PanK and CoA diphosphatase (nudix hydrolase) isoforms in the livers of wild-type and Pank1−/− mice.

The PanK1β transcript was the most abundant PanK mRNA in the wild type liver, and its level was set at 10. The abundance of all other PanK isoforms was expressed relative to PanK1β. The mRNA abundance of nudix hydrolases is reported relative to a cyclophilin calibrator. Each transcript was measured in triplicate for each mouse sample, and the combined results are shown, ± s.d. (number of mice).aND means not detectable.bNA means not analyzed.cMeans statistically significant difference between Pank1−/− and controls (pdMeans statistically significant difference between fed and fasted (p

野生型肝脏中，泛酸激酶1β转录本（PanK1β transcript）是丰度最高的泛酸激酶（PanK）mRNA，其表达水平被设定为10。其余所有泛酸激酶亚型（PanK isoforms）的mRNA丰度均以PanK1β为参照进行定量。nudix水解酶家族（nudix hydrolases）的mRNA丰度则以亲环蛋白（cyclophilin）作为内参校准物进行报告。每份小鼠样本均对各转录本进行三次重复检测，最终合并结果以均值±标准差（s.d.，standard deviation）表示，括号内标注小鼠数量。
aND：表示未检出（not detectable）。
bNA：表示未分析（not analyzed）。
c：表示Pank1基因敲除纯合子（Pank1−/−）与对照组之间存在统计学显著差异（p值未完整给出）。
d：表示进食组与禁食组之间存在统计学显著差异（p值未完整给出）。