RNA sequencing analysis of the sea lamprey brainstem after spinal cord injury and GABA or baclofen treatments [baclofen]
收藏干细胞与再生医学数据中心2022-02-20 更新2024-03-06 收录
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http://data.iscr.ac.cn/Article?id=c0fc2c7a5c2a6b88c94971ce2873ce2f
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We have previously shown that baclofen treatments inhibit caspase activation and promote axon regeneration in descending neurons of the sea lamprey brainstem after a complete spinal cord injury. Here, we repeated this treatment and performed Illumina RNA sequencing studies in the brainstems of control and baclofen treated animals.
我们先前的研究已证实，在完全性脊髓损伤后，巴氯芬（baclofen）处理能够抑制半胱天冬酶（caspase）激活，并促进七鳃鳗（sea lamprey）脑干下行神经元的轴突再生。本研究重复了该处理流程，并对对照组与巴氯芬处理组动物的脑干组织开展了Illumina RNA测序（Illumina RNA sequencing）相关研究。
提供机构：
University of Santiago de Compostela
创建时间：
2022-02-20
