HYPERBILIRUBINEMIA: A NEW DIAGNOSTIC MARKER FOR ACUTE APPENDICITIS AND ITS PART IN PREDICTING APPENDICULAR PERFORATION

Introduction:Acuteappendicitis is the commonest cause of Acute Surgical abdomen.Appendicectomy is the most frequently performed urgent abdominal operation and is often the first major procedure performed by a surgeon in training.

Aims&Objectives:The objectives of the study were-To study the relationship between hyperbilirubinemia and acute appendicitis and to evaluate its credibility as a diagnostic marker for acute appendicitis.

Materials&Methods:The study was conducted in the Department of General Surgery, HKEs Basaveshwar Teaching and General Hospital, kalaburagi attached to MahadevappaRampure Medical College, kalaburagi during the period of August 2022 to August 2023. A one year cross sectional study.

Results:A total of 100 patients with clinical diagnosis of acute appendicitis or appendicular perforation admitted in the Department of General surgery, HKEs Basaveshwar Teaching & General Hospital, kalaburagi attached to MahadevappaRampure Medical College, kalaburagi were studied.

Discussion:Acute appendicitis is the most common cause of acute abdomen in young adults. Appendicectomy is the most frequently performed urgent abdominal operation and is often the first major procedure performed by a surgeon in training.PPAbout 8% of people in Westerncountries have appendicitis at some time in their lifetime.

Conclusion: The present study suggests-Serum bilirubin levels appears to be a promising new laboratory marker for diagnosing acute appendicitis, however diagnosis of appendicitis remains essentially still - clinical. Its level come out tobe a credible aid in diagnosis of acute appendicitis and would be helpful investigation in decision making.

引言：急性阑尾炎（acute appendicitis）是急性外科急腹症最常见的病因。阑尾切除术（appendicectomy）是临床最常开展的急诊腹部手术，同时也常为外科受训医师完成的首例大型手术。

研究目的：本研究旨在探讨高胆红素血症（hyperbilirubinemia）与急性阑尾炎之间的关联，并评估其作为急性阑尾炎诊断标志物的临床可信度。

材料与方法：本研究于2022年8月至2023年8月期间，在隶属于卡拉布拉吉市马哈德沃帕·兰普尔医学院的HKEs Basaveshwar教学综合医院普通外科开展，为一项为期1年的横断面研究。

研究结果：本研究共纳入100例因临床诊断为急性阑尾炎或阑尾穿孔而入住该医院普通外科的患者进行分析。

讨论：急性阑尾炎是青年人群急性腹痛最常见的病因。阑尾切除术仍是临床最常实施的急诊腹部手术，同时也常为外科受训医师完成的首例大型手术。西方国家约8%的人群在其一生中的某个阶段会罹患阑尾炎。

结论：本研究结果显示，血清胆红素水平有望成为诊断急性阑尾炎的新型实验室标志物，但目前阑尾炎的诊断本质上仍依赖于临床评估。血清胆红素水平可作为急性阑尾炎诊断的可靠辅助依据，可为临床决策提供有价值的参考指标。