Collateral lethality occurs when loss of one paralog renders cancer cells dependent on the remaining paralog. Combining genome scale CRISPR/Cas9 screens coupled with RNA-sequencing in over 900 cancer

NIAID Data Ecosystem80

Morphological and elemental characterization of human Glioblastoma Multiforme by multiscale and multimodal synchrotron analysis

神经肿瘤学

胶质瘤微环境

We want to evaluate morphologic and elemental parameters of the human Glioblastoma Multiforme (GBM) brain tumor by using multi-scale and multi-modal synchrotron techniques, i.e. X-ray phase contrast t

DataCite Commons2025-02-17 更新60

Common Tumor Suppressive Signaling of Thyroid Hormone Receptor Beta in Breast and Thyroid Cancer Cells

肿瘤抑制机制

转录组学分析

The thyroid hormone receptor beta (TRÃ) is a tumor suppressor in multiple types of solid tumors, most prominently in breast and thyroid cancer. An increased understanding of the molecular mechanisms

NIAID Data Ecosystem90

Supplementary Material for: Cardiac Arrhythmias Associated with Brain Tumors: A Systematic Review

神经肿瘤学

心脏电生理学

Introduction: Brain tumors may disrupt cardiac autonomic regulation, leading to arrhythmias that complicate patient management. This review aims to synthesize evidence on the relationship between bra

DataCite Commons2025-10-28 更新60

Feedback Circuit among INK4 Tumor Suppressors Constrains Human Glioblastoma Development

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