Spontaneous mutagenesis in strains deficient in histone H3 K56 deacetylation.

With the exception of the first four strains, the strains are E134 (wild type) and its mutant derivatives. Fluctuation analyses and calculations of both mutation rates and 95% confidence intervals were performed as described in Materials and Methods. 95% confidence intervals are in parentheses. BY4742 strain lacks the his7-2 reporter. The difference between two mutation rates marked witha, b, or c a, b, or c is not statistically significant (ap = 0.17, bp = 0.06, and cp = 0.10).

除前四株供试菌株外，其余菌株均为E134（野生型，wild type）及其突变衍生株。波动分析（fluctuation analyses）以及突变率与95%置信区间（95% confidence intervals）的计算均按照《材料与方法》中的描述进行。95%置信区间以括号标注。BY4742菌株缺失his7-2报告基因（his7-2 reporter）。带有a、b或c标记的两组突变率之间的差异无统计学显著性（a对应P=0.17，b对应P=0.06，c对应P=0.10）。