Annexes to the scientific report on prioritisation of pesticides and target organ systems for dietary cumulative risk assessment based on the 2019–2021 monitoring cycle

Aiming at accelerating the implementation of cumulative risk assessment to pesticide residues, EFSA performed a two‐step prioritisation analysis, on individual pesticides and on target organ systems, that allows to identify (i) low‐priority substances expected to have a marginal contribution to cumulative risk, and (ii) high priority organ systems to be addressed in future cumulative risk assessments. The analysis encompassed 350 substances and 36 raw primary commodities of plant origin surveyed in the monitoring cycle 2019–2021, carried out in 30 population groups, covering 3 age classes, and 17 EU countries. Probabilistic exposure calculations, for chronic and acute effects, were executed on the occurrence and consumption data by a two‐dimensional procedure, modelling variability and uncertainty. 

The input data for the prioritsation of chronic and acute exposure risk assessment to pesticide residues and the output data produced are reported in the following annexes:

Annex A.1 – Input data for the prioritisation of chronic cumulative risk assessment to pesticide residues;Annex A.2 – Input data for the prioritisation of acute cumulative risk assessment to pesticide residues;Annex B.1 – Output data from the chronic exposure assessment of pesticides that have an EU-agreed health-based guidance value;Annex B.2 – Output data from the chronic exposure assessment of pesticides that have a tentative health-based guidance value;Annex B.3 – Output data from the acute exposure assessment of pesticides that have an EU-agreed health-based guidance value;Annex B.4 – Output data from the acute exposure assessment of pesticides that have a tentative health-basedguidance value;Annex C.1 – Output data from the combined exposure assessment of pesticides that may have chronic effects on theinvestigated target organ systems;Annex C.2 – Output data from the combined exposure assessment of pesticides that may have acute effects on theinvestigated target organ systems

Detailed information on methodology, results and conclusions are included in the full report 'Prioritisation of pesticides and target organ systems for dietary cumulative risk assessment based on the 2019–2021 monitoring cycle', DOI: 10.2903/j.efsa.2024.8554.

为加速农药残留累积风险评估的落地实施，欧洲食品安全局（EFSA）针对单一农药及靶器官系统开展了两步法优先性分析，可识别出（i）对累积风险贡献极小的低优先级物质，以及（ii）未来累积风险评估中需重点关注的高优先级靶器官系统。本次分析覆盖了2019-2021年监测周期内抽检的350种物质及36种植物源初级农产品，涵盖30个人群群组、3个年龄层级以及17个欧盟成员国。研究采用二维分析流程，基于农药检出数据与膳食摄入数据，针对慢性与急性健康效应开展概率暴露评估，并对变异与不确定性进行建模。

用于农药残留慢性、急性暴露风险评估优先性分析的输入数据，以及所生成的输出数据，将在以下附件中予以公布：
附件A.1 —— 农药残留慢性累积风险评估优先性分析输入数据；附件A.2 —— 农药残留急性累积风险评估优先性分析输入数据；附件B.1 —— 具有欧盟认可健康指导值的农药慢性暴露评估输出数据；附件B.2 —— 具有暂定健康指导值的农药慢性暴露评估输出数据；附件B.3 —— 具有欧盟认可健康指导值的农药急性暴露评估输出数据；附件B.4 —— 具有暂定健康指导值的农药急性暴露评估输出数据；附件C.1 —— 对所调研靶器官系统具有潜在慢性效应的农药联合暴露评估输出数据；附件C.2 —— 对所调研靶器官系统具有潜在急性效应的农药联合暴露评估输出数据

关于研究方法、结果与结论的详细信息，可参阅完整报告《基于2019-2021年监测周期的膳食累积风险评估用农药及靶器官系统优先性分析》，DOI: 10.2903/j.efsa.2024.8554。