NHLBI TOPMed: Children's Health Study (Effects of Air Pollution on the Development of Obesity in Children)

The Effects of Air Pollution on the Development of Obesity in Children (Meta-AIR) study was proposed to study a subset of the Children's Health Study (CHS) participants representing the extremes of long-term traffic-related air pollution exposure occurring in Southern California CHS communities. The primary aim of the Meta-AIR study was to investigate whether lifetime exposure to air pollution increases risk for obesity and metabolic dysfunction at 17-18 years of age. A total of 56 Hispanic White participants (16 asthma cases and 40 controls) were included in the TOPMed project.

空气污染对儿童肥胖发生的影响（Meta-AIR）研究，旨在纳入儿童健康研究（Children's Health Study, CHS）中，代表南加州CHS社区中长期交通相关空气污染暴露极端水平的参与者子集。该研究的主要目标为探究终身暴露于空气污染是否会增加17-18岁人群罹患肥胖及代谢功能障碍的风险。共计56名西班牙裔白人参与者（含16名哮喘病例与40名对照）被纳入TOPMed项目。